intrinsic activity वाक्य
उदाहरण वाक्य
मोबाइल
- The thesis developed the concepts of receptor affinity and intrinsic activity.
- Dichloroisoprenaline was the first " beta blocker "; it retains some intrinsic activity.
- The-pump has been shown to control and set the intrinsic activity mode of cerebellar Purkinje neurons.
- When the teams succeed, all the " winners " earn brief intrinsic activity rewards based on Premack's principle.
- Moderate stimulation ( intrinsic activities about half that of the reference standard, isoprenaline ) was observed in adipocytes from rat or hamster.
- Olodaterol is a nearly full ? 2 agonist, having 88 % intrinsic activity compared to the gold standard isoprenaline / isoproterenol ).
- An antagonist-like molecule with low intrinsic activity ( ia ) decreases the frequency of channel-opening and the permeability of ions.
- This resting potential undergoes rhythmic oscillations, which have been termed " slow waves ", and reflect intrinsic activity of slow wave potentials.
- Furthermore, pridopidine displays no detectable intrinsic activity, differentiating it from D 2 receptor agonists and partial agonists ( agents that stimulate receptor responses ).
- However, it has 100-fold lower estrogenic activity relative to estradiol, which may be due to differences in the intrinsic activity of the two compounds.
- Smyth, D . G . ( 1967 ) Carbamylation of amino and tyrosine hydroxyl groups : preparation of an inhibitor of oxytocin with no intrinsic activity on the isolated uterus.
- "' EVT-201 "'is a benzodiazepine ? 5 subunits and significantly less intrinsic activity in comparison to currently-marketed benzodiazepines and the Z-drugs.
- Moreover, due to partial agonism of the KOR, where it appears to possess significantly greater intrinsic activity relative to the MOR, diprenorphine can produce sedation as well as, in humans, hallucinations.
- However, in the presence of full agonists like testosterone or dihydrotestosterone ( DHT ), due to its lower intrinsic activity in comparison, it has antagonistic effects, and can behave more like an antiandrogen.
- However, due to its lower intrinsic activity in comparison, in the presence of full agonists like testosterone or dihydrotestosterone ( DHT ), 4-androstenediol has antagonistic actions, behaving more like an antiandrogen.
- An important accomplishment of Ari�ns was the establishment of experiments on isolated organs instead of the living animal ( " ex vivo " ), which quickly and reproducibly delivered data on the affinity and intrinsic activity of test substances.
- Taking a more sophisticated approach, receptor reserve is an integrative measure of the response-inducing capacity of an agonist ( in some receptor models it is termed intrinsic efficacy or intrinsic activity ) and of the signal amplification capacity of the corresponding receptor ( and its downstream signaling pathways ).
- "' Levallorphan "'( antagonist of the ?-opioid receptor ( MOR ) and as an agonist of the ?-opioid receptor ( KOR ), and as a result, blocks the effects of stronger agents with greater intrinsic activity such as morphine whilst simultaneously producing analgesia.
- Thus, the production of hepoxilins from 12 ( S )-HpETE may result from the intrinsic activity of platelet or leukocyte type 12-LOX's, require eLOX3, or even result from 12 ( " S " )-HpETE spontaneous ( and perhaps artifactual ) decomposition during isolation.
- DPN is a racemic mixture of two enantiomers, ( R )-DPN and ( S )-DPN . Relative to ( R )-DPN, ( S )-DPN has between 3-and 7-fold higher affinity for ER? and appears to have higher intrinsic activity in activating ER?.
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